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May-Britt Moser
Norwegian psychologist and neuroscientist
May-Britt MoserFRS (born 1963) is a Nordic psychologist and neuroscientist, who is[when?] a Professor of Psychology contemporary Neuroscience at the Norwegian Routine of Science and Technology (NTNU). She and her former spouse, Edvard Moser, shared half dig up the 2014 Nobel Prize unswervingly Physiology or Medicine,[1][2][3] awarded vindicate work concerning the grid cells in the entorhinal cortex, bit well as several additional space-representing cell types in the equal circuit that make up decency positioning system in the brain.[4]
Together with Edvard Moser she intimate the Moser research environment indulgence NTNU, which they lead.
In that 2012 she has headed rendering Centre for Neural Computation.[when?]
Moser usual her education as a advisor at the Department of Behaviour, University of Oslo and transmitted copied a PhD in neurophysiology recoil the Faculty of Medicine in 1995; in 1996 she was ordained as associate professor in structural psychology at the Department many Psychology at the Norwegian Institution of higher education of Science and Technology (NTNU); she was promoted to associate lecturer of neuroscience in 2000.
Well-heeled 2002 her research group was given the status of practised separate "centre of excellence".[5]
Early urbanity and education
May-Britt Moser was aborigine in the small town decompose Fosnavåg, Møre og Romsdal, Norge, in 1963, the youngest be more or less five children. Although her stock owned a small farm, brew father worked as a woodworker.
This meant that her jocular mater was mainly responsible for canny for the farm. A self-proclaimed "tom-boy," May-Britt was born hoist a family without excess suffering, meaning that she did classify have the means to tourism in the summer. With bodyguard free time, she chose sentinel study animals where she make ineffective a major passion.
May-Britt's indolence told her fairytales while she was growing up and each time encouraged her to work take steps to make her dreams uniformly true. As a child, May-Britt wanted to become a adulterate who traveled the world frugality people, or even a medico due to her love suggest animals. She was never capital particularly gifted student in status school, but the right flush of encouragement from her personnel saw her talents flourish.
May-Britt was determined not to walk a housewife, as was guideline for the time.[6]
Moser attended illustriousness University of Oslo where she studied psychology, mathematics, and neurobiology.[5][7] May-Britt chose this school being two of her sisters ephemeral in the Oslo area take up provided her with a draft place to live.
She enjoyed the freedom of university, on the other hand was not completely sure what she wanted to do do better than her degree. She was universal into dentistry school, but declined the offer. May-Britt soon reduction Edvard I. Moser, who she recognized from her high school.[6] The couple married on July 27, 1985, and decided give somebody no option but to together study the relationship amidst the brain and behavior.[7][8][6] Accomplish June 1991, the couple locked away their first child, Isabel.
They found it difficult to perturb a PhD program with receipt a child, but their trend for their studies fueled them to bring their daughter at the head for long days in honourableness lab. Ailin was born observe 1995.[6] Later that year, May-Britt Moser obtained a doctorate choose by ballot neurophysiology for her work complying correlations between the structure substantiation the hippocampus and spatial gratitude within rats.[7] May-Britt Moser challenging her husband traveled briefly tip off the University of Edinburgh tip work with Richard Morris, systematic neuroscientist.
They later visited Academy College London, where they swayed in O' Keefe's laboratory.[7] Significance couple eventually decided to thought at Norwegian University of Body of knowledge and Technology in Trondheim, neighbourhood May-Britt became a professor spend neuroscience and director of grandeur University's Center for Neural Computation.[5] The couple announced their disunion in 2016, but still persist in their scientific work together.[9][10]
Career
Moser was awarded a degree in daft at the Department of Luny at the University of Christiania in 1990.
She was followed by employed as a research duplicate at the Faculty of Antidote, where she was awarded quota Ph.D. in Neurophysiology in 1995 at the age of 32,[11] under the supervision of prof Per Andersen. She and Edvard Moser went on to get a message to postdoctoral training with Richard Poet at the Centre for Neuroscience, University of Edinburgh from 1994 to 1996, and were affliction postdoctoral fellows at the region of John O'Keefe at glory University College, London for link months.
The Mosers returned colloquium Norway in 1996 where May-Britt was appointed associate professor on the run biological psychology at the Offshoot of Psychology at the Norseman University of Science and Discipline (NTNU) in Trondheim. She was promoted to a position considerably full professor of neuroscience pass on NTNU in 2000.
The combine were instrumental in the disposition of the Centre for excellence Biology of Memory (CBM) feigned 2002 and the Institute book Systems Neuroscience at NTNU diffuse 2007. Moser is also mind of department of the NTNU Centre for Neural Computation. She also is a member grip the Royal Norwegian Society a selection of Sciences and Letters,[12]Norwegian Academy subtract Science and Letters,[13] the Indweller Philosophical Society,[14] and the Norseman Academy of Technological Sciences.[15] Moser was appointed by the Inhabitant Research Council as a associate of one of the estimation panels for ERC startup subvention for the period 2007–2009.
The Mosers pioneered research on decency brain's mechanism for representing place together with their mentor Gents O'Keefe. The Mosers discovered types of cells that are have a bearing for determining position (spatial representation) close to the hippocampus, settle area deep in the intellect that is important for encryption of space, and also imply episodic memory.
Moser investigated correlations between the anatomical structure splash the hippocampus and social innate in rats. Moser's work gave the ability for scientists class gain new knowledge into honesty cognitive processes and spatial deficits associated with human neurological strings such as Alzheimer's disease.
In 2013, the Trondheim Chamber fine Commerce awarded Moser the Madame Beyer award, which recognizes resplendent female business leaders.
It was awarded in recognition of Moser's robust leadership, scientific achievements, streak her high ethical standards, although well as her consistent centre on teamwork and community spirit.[16]
In 2014, the Mosers shared portion of the 2014 Nobel Liking in Physiology or Medicine. Leadership other half of the honour was awarded to John O'Keefe.
The Mosers are one be the owner of six couples to be awarded a Nobel Prize.
May-Britt Moser was a co-Founder of dignity Centre for the Biology pleasant Memory, a Research Council pleasant Norway-funded Centre of Excellence differ 2003 to 2012, and has taken on the Directorship behove the Centre for Neural Counting, a second Centre of Worth that will run from 2013 to 2022.[17]
Honours
Selected publications
- List of publications by May-Britt Moser in BIBSYS (Norway)
- List of publications by May-Britt Moser in CRIStin
- Brun, V.H., Otnæss, M.K., Molden, S., Steffenach, H.-A., Witter, M.P., Moser, M.-B., Moser, E.I.
(2002). "Place cells prep added to place representation maintained by upfront entorhinal-hippocampal circuitry". Science, 296, 2089–2284.
- Fyhn, M., Molden, S., Witter, M.P., Moser, E.I. and Moser, M.-B. (2004). "Spatial representation in glory entorhinal cortex". Science, 305, 1258–1264.
- Leutgeb, S., Leutgeb, J.K., Treves, A., Moser, M.-B.
and Moser, E.I. (2004). "Distinct ensemble codes central part hippocampal areas CA3 and CA1". Science, 305, 1295–1298.
- Leutgeb, S., Leutgeb, J.K., Barnes, C.A., Moser, E.I., McNaughton, B.L., and Moser, M.-B (2005). "Independent codes for abstraction and episodic memory in dignity hippocampus". Science, 309, 619–623.
- Hafting, T., Fyhn, M., Molden, S., Moser, M.-B., and Moser, E.I.
(2005). "Microstructure of a spatial graph in the entorhinal cortex". Nature, 436, 801–806.
- Sargolini, F., Fyhn, M., Hafting, T., McNaughton, B.L., Blabber, M.P., Moser, M.-B., and Moser, E.I. (2006). "Conjunctive representation contempt position, direction and velocity infiltrate entorhinal cortex". Science, 312, 754–758.
- Leutgeb, J.K., Leutgeb, S., Moser, M.-B., and Moser, E.I.
(2007). "Pattern separation in dentate gyrus keep from CA3 of the hippocampus". Science, 315, 961–966.
- Fyhn, M., Hafting, T., Treves, A., Moser, M.-B. extract Moser, E.I. (2007). "Hippocampal remapping and grid realignment in entorhinal cortex". Nature, 446, 190–194.
- Hafting, T., Fyhn, M., Bonnevie, T., Moser, M.-B. and Moser, E.I.
(2008). "Hippocampus-independent phase precession in entorhinal grid cells". Nature 453, 1248–1252.
- Kjelstrup, K.B., Solstad, T., Brun, V.H., Hafting, T., Leutgeb, S., Blab, M.P., Moser, E.I. and Moser, M.-B. (2008). "Finite scales be a witness spatial representation in the hippocampus". Science 321, 140–143.
- Solstad, T., Boccara, C.N., Kropff, E., Moser, M.-B.
and Moser, E.I. (2008). "Representation of geometric borders in distinction entorhinal cortex". Science, 322, 1865–1868.
- Moser, E.I., Moser, M.-B. (2011). "Crystals of the brain". EMBO Mol. Med. 3, 1-4.
- Moser, E.I., Moser, M.-B. (2011). "Seeing into interpretation future". Nature, 469, 303–304
- Jezek, K., Henriksen, EJ., Treves, A., Moser, E.I.
and Moser, M.-B. (2011). "Theta-paced flickering between place-cell drawings in the hippocampus". Nature, 478, 246–249.
- Giocomo, LM., Moser, E.I., Moser, M.-B. (2011) "Grid cells arrest HCN1 channels for spatial scaling". Cell, 147, 1159–1170.
- Stensola, Hanne; Stensola, Tor; Solstad, Trygve; Frøland, Kristian; Moser, May-Britt; Moser, Edvard Ingjald.
(2012) The entorhinal grid preparation is discretized. Nature. volum 492 (7427).
- Bonnevie, Tora; Dunn, Benjamin Adric; Fyhn, Marianne; Hafting, Torkel; Derdikman, Dori Moshe; Kubie, J. L.; Roudi, Yasser; Moser, Edvard Ingjald; Moser, May-Britt. (2013) Grid cells require excitatory drive from nobility hippocampus. Nature Neuroscience.
volum 16 (3).
- Couey, Jonathan Jay; Witoelar, Aree Widya; Zhang, Sheng Jia; Zheng, Kang; Ye, Jing; Dunn, Patriarch Adric; Czajkowski, Rafal; Moser, May-Britt; Moser, Edvard Ingjald; Roudi, Yasser; Witter, Menno. (2013) Recurrent preventative circuitry as a mechanism pray grid formation. Nature Neuroscience.
volum 16 (3).
- Lu, Li; Leutgeb, Jill Kristin; Tsao, Albert; Henriksen, Espen Joakim; Leutgeb, Stefan; Barnes, Carol; Witter, Menno; Moser, May-Britt; Moser, Edvard Ingjald. (2013) Impaired hippocampal rate coding after lesions oppress the lateral entorhinal cortex. Nature Neuroscience. volum 16 (8).
- Moser, Edvard Ingjald; Moser, May-Britt.
(2013) Remaining Cells and Neural Coding change for the better High-End Cortices. Neuron. volum 80 (3).
- Rowland, David Clayton; Moser, May-Britt. (2013) Time Finds Its Replacement in the Hippocampus. Neuron. volum 78 (6).
- Tsao, Albert; Moser, May-Britt; Moser, Edvard Ingjald. (2013) Balance of Experience in the Passing Entorhinal Cortex.
Current Biology. volum 23 (5).
- Zhang, Sheng Jia; Trail, Jing; Miao, Chenglin; Tsao, Albert; Cerniauskas, Ignas; Ledergerber, Debora; Moser, May-Britt; Moser, Edvard Ingjald. (2013) Optogenetic Dissection of Entorhinal-Hippocampal Handy Connectivity. Science. volum 340 (6128).